How to cure Kawasaki disease

Many friends often suffer from some diseases because they do not pay attention to their physical health, such as Kawasaki disease. According to experts, this disease is generally more common in children. So how to cure Kawasaki disease? Below we will introduce you to specific treatment methods, hoping to provide some help to friends in need.

Regarding the treatment of this disease, there are the following options.

1. Immunoglobulin. Recent studies have confirmed that early intravenous infusion of immunoglobulin plus oral aspirin can reduce the incidence of Kawasaki disease coronary artery aneurysms. It must be emphasized that the medication should be used within 10 days after the onset of the disease. The usage is daily intravenous infusion of immunoglobulin 400mg/kg, infused over 2 to 4 hours, for 4 consecutive days; at the same time, oral aspirin 50-100mg/kg·d, divided into 3 to 4 times, for 4 consecutive days, and then increased to 5mg/kg·d, taken all at once.

2. Aspirin. Early oral aspirin can control the acute inflammatory process and reduce coronary artery lesions, but no controlled studies have shown that aspirin treatment can reduce the incidence of coronary artery aneurysms. The dosage is 30-100 mg kg per day, divided into 3-4 times. Japanese doctors tend to use small doses, based on the fact that those who take large doses during the acute phase of Kawasaki disease believe that acute patients have reduced aspirin absorption and increased clearance, and only large doses can achieve anti-inflammatory effects. Take it for 14 days, and after the fever subsides, reduce it to 3-5 mg/kg per day, taken once, and the antiplatelet aggregation effect is fully achieved.

3. Corticosteroids. It has always been believed that adrenal cortex hormones have a strong anti-inflammatory effect and can relieve symptoms. However, it was later found that corticosteroids are prone to thrombosis, hinder the repair of coronary artery lesions, and promote aneurysm formation. Therefore, it is not appropriate to use corticosteroids such as prednisone alone for treatment. Unless there is a complication of severe myocarditis or a severe case of persistent high fever, prednisone and aspirin can be used in combination for treatment. In order to control the early inflammatory response of Kawasaki disease, corticosteroids are generally not used alone.

Kawasaki disease is a vasculitis syndrome that occurs in children aged 2 to 4 years old, and is more common in boys. In recent years, the incidence has increased. The biggest harm of Kawasaki disease is damage to the coronary arteries. It is the main cause of coronary artery disease in children and a potential risk factor for coronary heart disease in adulthood. In my country, the incidence is higher between July and September.