Polio is not usually directly inherited, but may indirectly increase the risk of infection due to a few familial hereditary immunodeficiency diseases. Polio is caused by the polio virus, and its main transmission route is through the digestive tract rather than genetic inheritance. Nevertheless, some people with low immunity will increase the risk of infection, so special attention should be paid to prevention. 1. Genetic factors Polio itself is not a hereditary disease, but certain inherited immune deficiencies increase children's susceptibility to the polio virus. For example, families with congenital immunodeficiency or inherited lymphocyte dysfunction may be more susceptible to infection when the virus spreads due to poor development of the immune system. In this case, the disease itself is not inherited, but the genetic constitution indirectly increases the risk of infection. 2 Environmental factors Virus transmission in the environment is the key to the onset of polio. The disease is most often transmitted through contaminated water, food, or contact with the hands of infected people. The risk of transmission is particularly high in areas or groups with poor sanitation. Improving sanitation, such as regular hand washing and drinking clean water, is an important preventive measure. 3 Physiological factors Children's immune systems are not fully developed yet, and their resistance to various viruses is generally weaker than that of adults. If children are not vaccinated on time, the chance of infection with the polio virus will increase significantly. Vaccination can effectively prevent virus invasion by stimulating the immune system to produce antibodies. 4 Trauma and secondary causes If a child's immune system is weakened due to trauma or certain serious illnesses, such as long-term use of immunosuppressive drugs, it may weaken the child's resistance to the polio virus, thereby increasing the chance of contracting polio. 5 Pathological process The specific pathological process of polio involves the polio virus invading the central nervous system and damaging motor neurons, which may cause limb paralysis in some patients. This process is usually not directly related to genetics, but its serious consequences remind people to pay attention to vaccination and virus transmission control. Vaccination is the most effective way to prevent polio, and children should be vaccinated on time. In daily life, good personal and family hygiene should also be maintained. If there is a history of immune system diseases in the family, geneticists and immunologists should be consulted for targeted evaluation and protective measures. |
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