What are the common tests for Kawasaki disease?

Regarding Kawasaki disease, there is a question that has always bothered our parents, that is, the commonly used examination methods for Kawasaki disease. If parents do not understand these methods, they will not be able to handle their children's examinations in a rational manner. I hope that the examination methods for Kawasaki disease explained to you today will be helpful and inspiring to you. Please see the introduction below.

How to diagnose Kawasaki disease

1. Blood test: White blood cell count increased, mainly neutrophils with left-shifted nuclei, mild anemia. Platelets began to increase in the second week. Erythrocyte sedimentation rate increased significantly, reaching more than 100 mm in the first hour. Serum protein electrophoresis showed increased globulin, especially α2 globulin. Albumin decreased. Serum transaminase increased.

2. Immunological examination: serum IgG, IgM, IgA, IgE and blood circulating immune complexes are elevated; TH2 cytokines are significantly elevated. C-reactive protein is elevated. Serum complement is normal or slightly elevated. Urine sediment shows leukocytosis and/or proteinuria.

3. Electrocardiogram: Non-specific ST-T changes are shown in the early stage; in pericarditis, there may be extensive ST segment elevation and low voltage; in myocardial infarction, the ST segment is significantly elevated, T wave inversion and abnormal Q wave are present, and PR and QR interval prolongation may also be shown.

4. Chest X-ray: It may show that the lung texture is increased and blurred or there are flake-like shadows, and the cardiac shadow may be enlarged.

5. Echocardiography: In the acute phase, pericardial effusion, enlarged left ventricular internal diameter, bicuspid aortic valve or tricuspid valve regurgitation may be seen; there may be coronary artery abnormalities such as coronary artery dilatation (diameter >3mm≤4mm is mild; 4-7mm is moderate), coronary artery aneurysm (≥8mm), and coronary artery stenosis.