What should I do if my newborn has severe jaundice? Severe neonatal jaundice is mainly related to neonatal hemolytic disease, sepsis, neonatal hepatitis syndrome, congenital biliary atresia, congenital hypothyroidism and other factors. General treatment, drug therapy, physical therapy and blood exchange therapy can be adopted if necessary. 1. General treatment Children with jaundice need to strengthen their nutrition during the illness. Parents should pay attention to regular breastfeeding to promote bilirubin excretion. At the same time, they also need to closely monitor the yellow staining of their children's skin. When the color deepens, they need to notify 2. Drug treatment Children with neonatal hemolytic jaundice need to use immunoglobulin G and human albumin to inhibit blood cell damage and reduce free bilirubin levels; children with septic jaundice should choose penicillin G, ampicillin, gentamicin, amikacin and other drugs to control infection based on the results of specimen culture; most neonatal hepatitis syndromes are caused by cytomegalovirus infection, and when necessary, ganciclovir and ursodeoxycholic acid can be used to control infection and improve liver function; children with congenital biliary atresia jaundice should undergo portojejunostomy, and ursodeoxycholic acid can promote bile excretion; children with congenital hypothyroidism jaundice should choose levothyroxine sodium tablets and thyroid tablets to increase thyroid hormone levels. 3. Physical therapy Blue light irradiation is a common physical treatment method for neonatal jaundice, which can promote the excretion of bilirubin in neonates. Treatment usually requires continuous irradiation. Pay attention to monitoring the serum bilirubin level and body temperature changes of children, observe children for adverse reactions such as fever, body temperature, diarrhea, rash, etc., pay attention to supplementing fluids to promote urine delivery, accelerate bilirubin excretion, and avoid dehydration of children. 4. Exchange blood therapy Blood exchange therapy is usually suitable for children with high jaundice levels, rapid progression, symptoms of kernicterus, or jaundice caused by severe neonatal hemolysis and severe sepsis. It can directly remove antibodies, free bilirubin and allergic red blood cells in children's plasma. |
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