What is the cause of low globulin? What disease causes low globulin?

Low globulin level is a relatively common condition. The main physiological causes are malnutrition and recent use of immune drugs; the main pathological causes are severe liver disease, congenital or acquired immune dysfunction and cholestasis.

Globulin is an essential element in our body. Its main function is immunity, so it is also called immunoglobulin. Under normal circumstances, the content of globulin has a standard range. If it is lower than the minimum standard, it can be considered as low globulin. So what is the reason for low globulin?

1. Physiological reasons for low globulin

1. Malnutrition

Low globulin levels may be caused by some physiological reasons, the most common of which is malnutrition. For example, many people have the habit of partial eating, always not eating this or that, which will lead to insufficient intake of protein or other nutrients, and low globulin levels will appear over time. The main component of globulin is protein, so everyone should ensure balanced nutrition and eat more protein-rich foods.

2. Drug reaction

The treatment of many diseases requires the use of immune drugs. If such drugs are used in the near future, the human immune system will undergo some changes. If corresponding examinations are performed at this time, it will be found that the globulin in the serum is low.

2. Pathological causes of low globulin

1. Severe liver disease

Low globulin may be caused by serious liver disease. Nowadays, many people suffer from liver inflammation. If there is no timely and effective treatment, the symptoms will worsen. The most common manifestation is a rapid decrease in globulin.

2. Weak immune function

If there is an immune deficiency that leads to low immune function, the globulin index will also be extreme. This immune deficiency includes congenital defects and acquired defects.

3. Cholestasis

Cholestasis can also lead to low globulin levels. If symptoms of cholestasis appear, inflammatory lesions will occur in the liver tissue. If these inflammations are not controlled in time, they will become more and more serious. Liver cells will also be greatly damaged, resulting in reduced liver synthesis and lower globulin levels. In some patients, the level will drop below 6%.