What causes kidney disease in children?

The main cause of childhood kidney disease is closely related to functional immune dysfunction. Simple nephropathy is a common type of primary kidney disease, which is more common in children aged two to seven years old. Nephritic nephropathy is also a type of primary kidney disease, which is more common in children over seven years old. In addition to the symptoms of kidney disease, it is also accompanied by microscopic hematuria and hypertension.

Common causes of kidney disease in children include:

1. Allergic constitution: A study of HLA antigens in various types of kidney diseases in children showed that 35.3% of nephrotic syndrome patients had allergic causes, while the control group had 6.7%. The cause of nephrotic syndrome was related to HLA-B40. It was reported that 40% of nephrotic syndrome patients had a history of allergic reactions.

2. Genetic causes: The incidence of nephrotic syndrome in children among siblings and twins is about 2% to 4%. Race and environmental differences are two important causes of nephrotic syndrome, which can increase the sensitivity of the onset of massive lesion type nephropathy.

3. Immune mechanism: It is well known that nephrotic syndrome is related to humoral immunity, immune complex formation, and cellular immunity. Its high incidence is related to many factors such as climate, astronomy, the type of childhood infection, and the genetic characteristics of the Arab population. These causes of nephrotic syndrome can affect the immune pathogenesis of kidney disease.

If you find that your child has kidney disease, you must go to the hospital for active treatment in time to avoid delaying the disease and causing greater harm to their health.