Cholestatic jaundice abnormal liver function

Cholestatic jaundice is caused by the accumulation of bilirubin in the blood due to the obstruction of bile excretion, which in turn causes abnormal liver function. Common causes include bile duct obstruction, hepatitis, drug reactions, etc. The treatment method should be selected according to the cause, including drugs, surgery or lifestyle adjustments.

1. Causes of abnormal liver function in cholestatic jaundice

The occurrence of cholestatic jaundice is related to many factors. Genetic factors may lead to congenital biliary atresia or abnormal development of the bile duct, affecting the normal excretion of bile. Environmental factors such as long-term exposure to toxic substances or infection with viral hepatitis such as hepatitis B and C can also cause cholestasis. Among physiological factors, changes in hormone levels during pregnancy may lead to cholestasis of pregnancy. Trauma such as bile duct injury or surgical complications may also cause bile excretion disorders. Pathological factors include bile duct stones, cholangitis, cirrhosis, etc., which may develop into liver cancer in severe cases.

2. Treatment of abnormal liver function in cholestatic jaundice

Treatment methods vary for different causes. In terms of drug treatment, commonly used drugs include ursodeoxycholic acid to promote bile excretion, antibiotics to treat infection, and antiviral drugs for viral hepatitis. Surgical treatment is suitable for patients with bile duct obstruction or stones. Common surgical methods include biliary stent implantation, biliary drainage, cholecystectomy, etc. Lifestyle adjustments are also crucial. Patients are advised to avoid high-fat diets and choose light and easily digestible foods, such as oatmeal, vegetable soup, steamed fish, etc. Moderate exercise such as walking and yoga can help improve liver function, but strenuous exercise should be avoided.

3. Medical advice and precautions

If you experience symptoms such as yellow skin, dark yellow urine, and fatigue, you should seek medical attention immediately, especially if you have a fever or abdominal pain. The doctor will make a clear diagnosis based on liver function tests and imaging tests such as ultrasound and CT. During treatment, you need to have your liver function checked regularly, take medication as directed by your doctor, and avoid stopping or changing medication on your own. For patients with chronic liver disease, long-term monitoring of changes in the condition is required to prevent complications.

Cholestatic jaundice and abnormal liver function are diseases that require timely intervention. Early diagnosis and treatment are crucial to improving prognosis. Through medication, surgery and lifestyle adjustments, most patients can effectively control the disease. Patients are advised to maintain healthy living habits, have regular physical examinations, and seek medical treatment in a timely manner if problems are found to avoid worsening of the disease.