What is Kawasaki disease and how to check it?

We should take disease prevention measures in our daily lives to stay away from many unnecessary troubles. For example, Kawasaki disease requires active treatment to get better as soon as possible. So how to get Kawasaki disease and how to check it? I hope the following introduction will be of some help to you.

In the acute phase, the total white blood cell count and percentage of granulocytes increase, and the nuclei shift to the left. Mild anemia is seen in more than half of the patients. The erythrocyte sedimentation rate increases significantly, reaching more than 100 mm in the first hour. Serum protein electrophoresis shows an increase in globulin, especially a significant increase in α2 globulin. Albumin decreases. IgG, IgA, and IgA increase. Platelets begin to increase in the second week. The blood is in a hypercoagulable state, and the antistreptolysin O titer is normal. Rheumatoid factor and antinuclear body are both negative. C-reactive protein increases.

Serum complement is normal or slightly elevated. Urine sediment may show leukocytosis and/or proteinuria. Electrocardiogram may show a variety of changes, with ST segment and T wave abnormalities being the most common, and may also show prolonged PR and QR intervals, abnormal Q waves, and arrhythmias. Two-dimensional echocardiography is suitable for cardiac examination and long-term follow-up. Various cardiovascular lesions such as pericardial effusion, left ventricular enlargement, mitral regurgitation, and coronary artery dilatation or aneurysm formation can be found in half of the patients.

It is best to check once a week during the acute and subacute phases of the disease. It is the most reliable non-invasive method for monitoring coronary artery aneurysms. In cases of aseptic meningitis, the lymphocyte count in the cerebrospinal fluid can be as high as 50-70/mm3. In some cases, serum bilirubin or alanine transaminase may be slightly elevated. Bacterial culture and virus isolation are both negative.

The above content is an introduction to the relevant knowledge about the examination of Kawasaki disease. In life, we must learn more about the relevant knowledge, do more preventive work, pay more attention to a light diet, do not eat spicy or irritating food, pay more attention to rest, and drink more warm water.