What to do about trehalase deficiency How to prevent trehalase deficiency

Lactase can break down lactose into galactose and glucose. Due to the lack of lactase, patients only absorb a small amount of disaccharides after eating lactose, and the rest enter the lower part of the small intestine. The bacteria in the intestinal cavity ferment the disaccharides to produce organic acids such as lactic acid, carbon dioxide and nitrogen. The unabsorbed disaccharides increase the osmotic pressure in the intestinal cavity, and the intestinal water absorption is reduced, causing diarrhea. The effect of organic acids on the intestines causes the discharge of acidic feces, and due to excessive gas production, it causes abdominal distension and bowel sounds.

The main thing is to restrict diet and abstain from milk and foods containing lactose. In mild cases, milk should be limited, and in severe cases, it should be completely forbidden. Infants can be given sugar-free milk or lactase. Sucrose-isomaltase deficiency patients should limit sucrose intake and, if necessary, starch intake. Secondary disaccharidase deficiency is often a multiple enzyme deficiency. Damage to the brush border enzymes of the small intestine is secondary to other diseases involving the intestine, such as adult milk.

There are many disaccharidases in the small intestinal mucosa of normal people, such as lactase, which can decompose lactose into galactose and glucose; maltase, which can decompose maltose into glucose and isomaltose; isomaltase, which can decompose isomaltose into two molecules of glucose; sucrase, which can decompose sucrose into glucose and fructose; and trehalase, which can decompose trehalose into two molecules of glucose. For some reason, the lack of disaccharidases causes the digestion and absorption of disaccharides to be impaired, leading to diarrhea. This disease is not uncommon in clinical practice, but it is often not taken seriously.