How to prevent severe pseudohypertrophic malnutrition? What to do if you have pseudohypertrophic malnutrition?

The impact of severe pseudohypertrophic malnutrition on people's health cannot be ignored. It has a certain genetic tendency and is very harmful. Prevention of this disease is far more effective than treatment. So, how to effectively prevent and treat severe pseudohypertrophic malnutrition?

1. Genetic counseling and carrier detection. Eugenics is an active and effective way to prevent the occurrence of this disease. For people with a family history of muscular dystrophy, they should seek a specialist for detailed family tree analysis. Among the four types of muscular dystrophy, pseudohypertrophic Duchenne type (DMD) is the most harmful to children's health, so carrier detection has great guiding significance for the prevention of Duchenne type (DMD) and marital status.

2. Detection of creatine phosphokinase (CPK). In patients with pseudohypertrophic muscular dystrophy, creatine phosphokinase (CPK) in serum increases, and activity determination can identify suspected carriers of some disease genes. Especially in Duchenne patients, about 60-80% of confirmed carriers and highly suspected carriers have increased creatine phosphokinase activity.

3. Prenatal gender determination. Prenatal gender determination is of great significance for high-risk fetuses in families with muscular dystrophy. Female carriers and male patients with muscular dystrophy have the characteristics of Duchenne type (DMD). Therefore, pregnant women suspected of being Duchenne type (DMD) carriers should undergo amniotic fluid examination in the late pregnancy to detect whether there are mutations in their gene loci. For pregnant women who are Duchenne type (DMD) carriers, after confirming that the baby is a boy, fetal blood should be drawn with a fetal scope to check creatine phosphokinase (CPK) or serum myoglobin (Mb) before deciding whether to terminate the pregnancy.

Treatment

1. Physical therapy: Clinical practice shows that although proper physical exercise and full movement of joints cannot cure this disease, it can at least delay the occurrence of more serious muscle atrophy, muscle weakness and joint contracture. Therefore, encouraging patients to do as much activity as possible plays a more important role in the treatment of this disease.

2. Tuina massage: Massage for this disease generally includes using appropriate techniques to stimulate the relevant meridian points to adjust the functions of the body and internal organs, and assisting patients in performing necessary functional exercises on various joints to delay the occurrence of muscle atrophy and prevent joint contracture. In many cases, the latter is more important than the former.

3. Acupuncture: Strictly speaking, patients with this disease should be treated with caution with acupuncture, especially with body acupuncture. When acupuncture is necessary, it is important to pay attention to the intensity of acupuncture stimulation. Patients with this disease should not use strong stimulation.

4. Targeted treatment: Nerve targeted repair therapy allows nerve growth factor to act on the damaged part through intervention, activating dormant nerve cells, achieving self-differentiation and renewal of nerve cells, replacing damaged and dead nerve cells, rebuilding neural circuits, and promoting organ redevelopment.