How to diagnose neonatal jaundice

What is neonatal jaundice? What are the characteristics of neonatal jaundice? The editor below will give you a detailed introduction.

Clinically, when encountering cases of neonatal jaundice and hemolytic anemia, we should think of neonatal jaundice caused by glucose-6-phosphate dehydrogenase (G6pD) deficiency, especially in non-high-incidence areas. The clinical characteristics of this disease are that the baby is not jaundiced at birth, and jaundice begins to appear 24 hours later. There is also evidence of hemolysis, and the liver and spleen are not enlarged. These can be distinguished from neonatal jaundice of other natures. Further tests on G6pD deficiency can confirm the diagnosis.

If neonatal jaundice is accompanied by hepatosplenomegaly, it should be suspected that the jaundice and anemia may be caused by alloimmunization or infection.

Isoimmune hemolytic disease, jaundice and anemia are present at birth due to incompatibility of maternal and fetal blood types. The two diseases can be clearly differentiated by identifying the maternal and fetal blood types and conducting serological tests, anti-human globulin tests and various tests related to G6pD deficiency.