What is jaundice 125 and how to deal with it

Generally speaking, if the jaundice is 125, it is a normal condition. We know that for infants and young children, once the jaundice is too high, it will often lead to more serious conditions, especially newborns will show more or less symptoms of jaundice. Most newborns' jaundice is physiological jaundice, which does not require treatment at this time, just emphasize rationalization. However, if it is pathological jaundice, it must be treated with formal methods.

Jaundice 125

125 divided by 27 is normal. The jaundice values ​​of children of different gestational ages, different ages, and different diseases are different. That is to say, the normal jaundice value of each child is different every day after birth. It needs to be confirmed based on the specific situation of the child. However, if it is based on the general conventional unit, it should be within the normal range.

Causes of neonatal jaundice

When the baby is still a fetus, the placenta supplies blood and oxygen. After the baby is separated from the mother, it starts to breathe with its own lungs to obtain oxygen. The hypoxic environment in the body changes and no longer needs so many red blood cells. At this time, bilirubin is produced and may be excessive. The excess bilirubin cannot be excreted from the body through the immature enzyme system. It flows with the blood to various parts of the baby's body, and is reflected in external signs, that is, the baby's skin and sclera turn yellow. This phenomenon is called neonatal jaundice.

1. Excessive bilirubin production

(1) Excessive destruction of red blood cells: The fetus is in a low-oxygen environment in the mother's womb, and the red blood cells increase in compensation, but their lifespan is short. After birth, the blood oxygen content increases and the excessive red blood cells are quickly destroyed.

(2) High heme oxygenase content: The content is high within 7 days after birth, and the potential for producing bilirubin is high.

2. Immature liver function

(1) Poor liver ability to absorb bilirubin: Insufficient levels of Y and Z proteins in liver cells result in insufficient liver absorption of bilirubin.

(2) Poor liver function of conjugating bilirubin: The content of glucuronyl transferase in the liver is low and its activity is insufficient, resulting in poor function of forming conjugated bilirubin.

(3) Poor liver excretion of bilirubin: Poor liver excretion of conjugated bilirubin can easily lead to cholestasis.

3. Characteristics of enterohepatic circulation: When a newborn is born, the normal intestinal flora has not yet been established and cannot convert the bilirubin entering the intestine into urobilinogen (fecal bilirubin).

Due to the above characteristics, the ability of newborns to absorb, bind and excrete bilirubin is significantly inferior to that of adults, and bilirubin is produced more but excreted less, so jaundice is very likely to occur. Jaundice will be aggravated when the baby is in hypoxia, delayed meconium excretion, delayed feeding, vomiting, dehydration, acidosis, cephalohematoma, etc.