What are the three types of hand, foot and mouth disease?

Summer is a high-incidence season for bacteria. Various bacteria breed quickly and cause babies to be infected with some diseases. Most patients have mild symptoms. Hand, foot and mouth disease is one of the diseases that babies suffer from due to bacterial infection. Hand, foot and mouth disease is a common infectious disease caused by a variety of enteroviruses. Babies with hand, foot and mouth disease cough and drool, do not like to eat, and have some small blisters in their throats. The most typical onset of the disease is moderate fever. So, what are the three types of hand, foot and mouth disease?

1. Coxsackievirus A: It is more common in children, with 21.7% of infections in adults. In addition to the above clinical manifestations, the main features are acute fever and rash. Meningoencephalitis is accompanied by Guillain-Barré syndrome and acute viral cardiomyopathy.

2. Coxsackievirus B: Infection causes characteristic infectious chest and rib pain (epidemicpleurodynia), the so-called Bornholm's disease, which may be accompanied by meningoencephalitis, myocarditis, fever, Guillain-Barré syndrome, hepatitis, hemolytic anemia and pneumonia.

3. Enterovirus CoxA16 hand, foot and mouth disease: There are more than 20 types of enterovirus that can cause hand, foot and mouth disease, among which Coxsackievirus A16 (CoxA16) and enterovirus 71 (EV71) are the most common. The pathogen of hand, foot and mouth disease discovered in the early stage is mainly CoxA16. Generally speaking, the sequelae of Coxsackie A16 are less than those of EV71.

4. Enterovirus 71 hand, foot and mouth disease

Fever is a common clinical symptom of EV71 infection in infants and young children. Most of the patients are infants under 6 months old. Acute respiratory disease is another common clinical symptom of EV71 infection. It includes some common respiratory symptoms, such as pharyngitis, asthma, bronchiolitis and pneumonia. The age of onset is generally 1 to 3 years old and requires hospitalization. EV71 involvement of the nervous system often occurs in children under 5 years old, with the highest incidence in children aged 1 to 2 years old. The main manifestations are aseptic meningitis, encephalitis and paralytic diseases, which often occur in children under 5 years old, with the highest incidence in infants under 1 year old. The clinical manifestations vary, and the severity of the disease varies. It is generally manifested as clonus, vomiting, ataxia, intention tremor, nystagmus and emotional indifference. Brain MRI and electroencephalogram examinations can help to clarify the severity of the disease.