What tests should be done for mumps

Mumps is a disease that is not unfamiliar to everyone. It is a viral infectious disease. This disease is highly contagious. Therefore, once a mumps patient is diagnosed, he or she must be isolated and treated immediately. Mumps patients must undergo relevant examinations regularly during the treatment process to keep abreast of the dynamics of the disease. Below I will introduce the common examination methods for mumps.

Laboratory tests:

1. Peripheral blood white blood cell count is mostly normal or slightly increased, and lymphocytes are relatively increased. When there are complications, the white blood cell count may increase, and occasionally there will be leukemoid reactions.

2. Serum and urine amylase determination: 90% of patients have mild to moderate increase in serum amylase and urine amylase is also increased, which is helpful for diagnosis. The increase in amylase is often proportional to the degree of parotid swelling, but its increase may also be related to lesions of the pancreatic and small intestinal serous glands.

3. Serological examination

(1) Neutralizing antibody test: A low titer such as 1:2 indicates active infection.

In recent years, the gel hemolysis test has been used, which is basically consistent with the neutralization test and is simpler and faster than the detection of neutralizing antibodies, but the method still needs further improvement.

(2) Complement fixation test: It has auxiliary diagnostic value for suspected cases. If the titer of two serum samples (early stage and 2-3 weeks of the disease) increases by more than 4 times, or the titer of one serum sample reaches 1:64, it has diagnostic significance. If conditions permit, it is advisable to measure S antibody and V antibody at the same time. An increase in S antibody indicates a recent infection, while an increase in V antibody but no increase in S antibody only indicates a previous infection.

(3) Hemagglutination inhibition test: The amniotic fluid and allantoic fluid of chicken embryos infected with the virus can cause the chicken's red blood cells to agglutinate. The convalescent serum of mumps patients has a strong inhibitory effect on agglutination, while the inhibitory effect of early serum is weaker. If the titer of two measurements differs by more than 4 times, it is considered positive.

4. Virus isolation In early cases, mumps virus can be isolated from saliva, urine, blood, cerebrospinal fluid, brain, thyroid and other tissues. The procedures are complicated and there is no condition for widespread implementation.

5. When the kidneys are affected, proteinuria, red and white blood cells, etc. may appear in the urine, and even changes in urine similar to nephritis may occur.

Other auxiliary examinations:

When combined with myocarditis, the electrocardiogram shows: arrhythmia, flat T waves, and depressed ST segment.

Through the introduction of the above content, I believe that everyone has a clearer understanding of the common examination methods for mumps. Common examination items for mumps include peripheral blood count, serological examination, etc. I hope that mumps patients can actively cooperate with the treatment. I wish everyone a speedy recovery and a healthy and happy life.