What tests can be used to detect Kawasaki disease?

What tests can be used to screen for Kawasaki disease? Kawasaki disease is also a relatively dangerous disease, so everyone needs to understand the knowledge in this area. Parents are most worried about their children's physical health. When children suffer from Kawasaki disease, many symptoms will appear. We need to understand the relevant knowledge, respond with caution, and face the disease correctly. Let us take a look at the examination items for this disease, I hope it can help you.

In the acute phase, the total white blood cell count and percentage of granulocytes increase, and the nucleus shifts to the left. Mild anemia is seen in more than half of the patients. The erythrocyte sedimentation rate increases significantly, reaching more than 100 mm in the first hour. Serum protein electrophoresis shows an increase in globulin, especially α2 globulin. Albumin decreases. IgG, IgA, and IgA increase. Platelets begin to increase in the second week. The blood is in a hypercoagulable state, and the titer of antistreptolysin O is normal.

Rheumatoid factor and antinuclear bodies are negative. C-reactive protein is elevated. Serum complement is normal or slightly elevated. Urine sediment shows leukocytosis and/or proteinuria. Electrocardiogram shows a variety of changes, with ST segment and T wave abnormalities being the most common, and may also show prolonged PR and QR intervals, abnormal Q waves and arrhythmias. Two-dimensional echocardiography is suitable for cardiac examination and long-term follow-up. Various cardiovascular lesions such as pericardial effusion, left ventricular enlargement, mitral regurgitation and coronary artery dilatation or aneurysm formation can be found in half of the patients.

It is best to check once a week during the acute and subacute phases of the disease. It is the most reliable non-invasive method for monitoring coronary artery aneurysms. In cases of aseptic meningitis, the lymphocyte count in the cerebrospinal fluid can be as high as 50-70/mm3. In some cases, serum bilirubin or alanine transaminase may be slightly elevated. Bacterial culture and virus isolation are both negative.

The above content is an introduction to the relevant knowledge about the examination items for Kawasaki disease. The harm after the occurrence of this disease cannot be underestimated. We must pay attention to it, learn more about relevant knowledge, do more preventive work in daily life, pay more attention to children's hygiene, and wash and change clothes regularly.