Does Kawasaki disease affect pregnancy?

Does Kawasaki disease affect pregnancy? When it comes to Kawasaki disease, many people may be unfamiliar with it. This is an acute febrile rash disease in children that is common in infants under 5 years old, with systemic vasculitis as the main lesion. The high-risk group for this disease is children. The cause of the disease is still unknown, but it is clear that it will not affect pregnancy. Let us take a closer look at it.

Although Kawasaki disease does not affect pregnancy, the impact of the disease on the child is worthy of our attention. Pediatric mucocutaneous lymph node syndrome, also known as Kawasaki disease, was first reported by Japanese doctor Tomisaku Kawasaki in 1967 and named after him. This disease is an acute febrile rash disease in children with systemic vasculitis as the main lesion. The high-risk age is infants and young children under 5 years old, more boys than girls, and it is rare in adults and children under 3 months old.

Clinical manifestations include fever, rash, non-purulent cervical lymphadenopathy, conjunctival hyperemia, diffuse congestion of oral mucosa, bayberry tongue, palmoplantar erythema, and edema of hands and feet. Because this disease can cause serious cardiovascular complications, it has attracted people's attention. The incidence rate of untreated children is 20% to 25%.

In addition, some cases have early lymphadenopathy, which is unilateral or bilateral, non-suppurative, and subsides after a few days. Sometimes the swelling spreads to the submandibular area, and is even misdiagnosed as mumps. The lymphadenopathy is limited to the anterior triangle of the neck, is painless, and rarely spreads to other parts. In the second week of the disease, some children have peeling of the hands and feet, which starts from the transition of the nail bed, and some may first show perianal desquamation.

The prognosis of this disease is generally good, and most children can recover on their own, but 5% to 9% of children with Kawasaki disease may develop coronary artery aneurysms. They may die from rupture of coronary artery aneurysms, thrombotic occlusion, myocardial infarction or myocarditis. Currently, the mortality rate has dropped to less than 1%, and about 2% of children will relapse.