Why are mothers with blood type O more likely to have jaundice?

If a mother with type O blood has high jaundice, it may be due to pregnancy cholestasis or infant cholestasis. Most hemolytic diseases can cause jaundice, and the degree of jaundice is very high. If the child born to a mother with type O blood is the first child, the chance of hemolytic disease is about 40%-50%, and the chance of hemolytic disease in the second and third children will increase to a certain extent. The specific analysis is as follows:

1. Cholestasis of pregnancy:

Pregnant women generally produce a large amount of estrogen in their bodies. High estrogen may reduce the activity of liver enzymes, cause bile acid metabolism disorders, and cause skin itching, yellowing, and other phenomena, which may also affect the growth and development of the fetus. Most cases of pregnancy-related cholestasis occur in the second and third trimesters, and generally require treatment with ursodeoxycholic acid; elevated transaminase levels may require treatment with bicyclol tablets; skin itching can be treated with drugs such as calamine lotion.

2. Infant Cholestasis:

1. Hemolytic jaundice: If the mother is type O blood and the baby is type A or type B blood, the baby may experience hemolytic reaction, often accompanied by fever, lack of energy, jaundice and other symptoms. It can usually be treated with drugs, such as glucocorticoids, immunosuppressants, folic acid, etc.; severe cases may require surgical treatment.

2. Physiological jaundice: If neonatal jaundice occurs, the probability of physiological jaundice is relatively high; the disease generally subsides on its own with age; when the disease occurs, it should be treated under the guidance of a doctor. Generally, blue light irradiation therapy can promote the decomposition of bilirubin in the body and alleviate the symptoms of jaundice.

When jaundice occurs, care should be taken to exclude pathological jaundice and treatment should be sought under the guidance of a doctor to avoid worsening of the condition.