What is severe Kawasaki disease?

Although Kawasaki disease, also known as mucocutaneous lymph node syndrome, is an acute, febrile, rash-causing pediatric disease with systemic vasculitis as the main pathology, it is more common in infants and young children, with 80% being under 5 years old.

If this treatment is not given, 1/4 of the children may develop coronary artery disease, including coronary artery dilatation, stenosis, and aneurysm, which is one of the most common causes of acquired heart disease in children. Therefore, severe Kawasaki disease may be considered serious only if it is accompanied by coronary artery disease or heart disease.

In fact, the cause of Kawasaki disease is still unclear. There are infection theories and immune theories. Anyway, it is controversial and not very clear. People think that some changes in vasculitis are caused by some infection, but whether it is caused by infection or not is not clear. It is a symptomatic diagnosis. How to diagnose it is that the fever lasts for more than 5 days, including 5 days, that is, more than 5 days, and four of the following five criteria appear:

The first is conjunctival congestion, but no exudate;

The second is changes in the mouth, lips, tongue, and mucous membranes, such as congestion, dryness, chapped skin, and bayberry tongue.

The third is the changes in the extremities, edema, erythema, desquamation, erythema multiforme on the skin of the trunk, and swollen lymph nodes in the neck. In addition to the fever for more than five days and the ineffectiveness of antibiotic treatment, if there are four of the following five conditions, it can generally be diagnosed. Cardiac ultrasound is one of the items that must be checked. If I don’t have these typical symptoms, but I have a fever for more than five days, I have mucosal congestion, and I have several, but my cardiac ultrasound shows coronary artery dilation, then I will definitely be diagnosed and confirmed.