What tests should be done for infants with Hirschsprung's disease?

The diagnosis of Hirschsprung's disease in infants requires multiple examinations, including X-ray angiography, anorectal pressure measurement and biopsy. It is recommended to see a doctor as soon as possible to determine the condition and treatment plan.

Hirschsprung's disease is an intestinal disease caused by abnormal development of ganglion cells, which usually presents as intestinal obstruction, difficulty passing stool, or severe constipation in the neonatal period. Due to defects in intestinal nerve innervation, some areas of the intestine cannot move normally, resulting in stool accumulation and colon expansion. This problem usually develops symptoms within a few days after birth, but the specific manifestations may vary depending on the degree of blockage.

Diagnosis requires the use of imaging and laboratory tests. Commonly used X-ray barium enema can observe the site of colon dilation and stenosis, which is an important tool for evaluating lesions. At the same time, anorectal pressure measurement can determine whether there are abnormalities in nerve reflexes, which is a key test for evaluating nerve function. The final diagnosis still needs to rely on pathological biopsy to confirm the diagnosis by detecting the distribution of ganglion cells in the intestinal wall. Although these examinations sound complicated, they are important means to help doctors understand the condition.

Parents should be aware that if a newborn baby is unable to defecate, has abdominal distension, or has abnormal bloody or mucous stools after birth, they should take the baby to the hospital for examination in time. In addition, regular examination of the baby's bowel movements and paying attention to whether the abdomen is obviously swollen or vomiting repeatedly can also help detect problems early. After the diagnosis is confirmed, the doctor usually decides on the treatment plan based on the condition, and surgery is a common cure. Early examination and treatment are important measures to ensure the health of the baby.