Physical examination method for poliomyelitis

Polio is a common childhood disease. Most patients are between 1 and 6 years old. Children at this age cannot express themselves, so many parents ignore the symptoms in their children. As a result, when the disease is discovered, it is already in the middle and late stages, which is of no help to the treatment of the disease. So, what are the physical examination methods for polio? The following is a detailed introduction for everyone.

1. Cerebrospinal fluid: Most of them are abnormal before paralysis. The appearance is slightly turbid, the pressure is slightly increased, the number of cells is slightly increased (25-500/mm3), neutrophils are more in the early stage, and mononuclear cells are mainly in the later stage. After the fever subsides, it quickly returns to normal. Sugar may increase slightly, chloride is mostly normal, protein increases slightly, and lasts for a long time. In a few patients, the cerebrospinal fluid can always be normal.

2. Peripheral blood picture: Most white blood cells are normal, but may increase in the early stage and during secondary infection, mainly neutrophils, and the erythrocyte sedimentation rate increases in the acute phase.

3. Virus isolation or antigen detection: within 1 week of onset, the virus can be isolated from the nasopharynx and feces. The feces can remain positive for 2 to 3 weeks. Early isolation of the virus from blood or cerebrospinal fluid is more significant. Tissue culture isolation is generally used. In recent years, PCR has been used to detect enterovirus RNA faster than tissue culture.

4. Serological examination: The titer of type-specific immune antibodies can reach a peak at the end of the first week, especially the specific IgM rises faster than IgG. Neutralization test, complement fixation test and enzyme labeling can be used to detect specific antibodies. Among them, neutralization test is more commonly used because it has a longer positive period. A 4-fold or more increase in the titer of two sera can be confirmed. The complement fixation test turns negative quickly. If it is negative as expected and the neutralization test is positive, it often indicates a past infection; if both are positive, it indicates a recent infection. Recently, the use of immunofluorescence technology to detect antigens and specific IgM monoclonal antibody enzyme labeling method has helped early diagnosis

Through the above understanding of the physical examination methods for polio patients, we clearly understand the examination methods for polio, and the side effects are small. A warm reminder: if you have polio, you should go to the hospital for treatment in time to avoid delaying the disease.