Neonatal jaundice is mostly a physiological problem, and most cases do not require drug intervention. Observation or appropriate adjustment of feeding methods can help the jaundice subside. If the situation is more serious, such as lasting too long or pathological jaundice, specific drugs or other treatments such as phototherapy or albumin infusion need to be used under the guidance of a doctor. 1 Types and causes of neonatal jaundice Neonatal jaundice can be divided into two types: physiological and pathological. Physiological jaundice: It appears about 2-3 days after birth and gradually disappears on its own within 2 weeks. It is caused by the destruction of the newborn's red blood cells and the incomplete maturity of the liver, which leads to the inability to quickly metabolize bilirubin. It is a normal physiological phenomenon. Pathological jaundice: mostly caused by bile duct obstruction, infection, hemolysis or congenital metabolic disease. It is characterized by severe jaundice that lasts for more than 2 weeks and requires early diagnosis and intervention treatment. 2 Clinical drug treatment methods For pathological jaundice, drug treatment should be performed under the advice of a doctor. Commonly used drugs include: Phenobarbital: It can enhance the liver's ability to metabolize bilirubin, but it needs to be used with caution and strictly according to the doctor's prescription. Albumin injection: For severe jaundice caused by hyperbilirubinemia, albumin can be infused to reduce the level of free bilirubin. Immunoglobulin: Children with hemolytic jaundice may need intravenous immunoglobulin to suppress the destructive effects of antibodies. 3Home care and supportive care Frequent feeding: Breastfeeding helps promote intestinal peristalsis and excrete bilirubin. Feed 8-12 times a day and increase fluid intake. Phototherapy: Using blue light irradiation under hospital guidance can quickly improve bilirubin levels. Phototherapy is often used when jaundice values are high but not suitable for drug treatment. Dietary adjustment: If breastfeeding does not improve jaundice, appropriate supplementation with formula milk can be performed under the guidance of a professional doctor to reduce possible breast milk jaundice. Most neonatal jaundice is physiological, so parents do not need to worry too much. They should pay attention to the progression of jaundice, especially the extent of yellowing of the skin and sclera, appetite, mental state, etc. If pathological jaundice is suspected or the jaundice is gradually getting worse, the patient should be seen as soon as possible, and blood bilirubin should be tested. After a clear diagnosis, comprehensive treatment should be carried out to ensure the health of the newborn. |
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