Is muscular dystrophy hereditary?

Muscular dystrophy is a hereditary disease with many clinical types, including pseudohypertrophic, scapulohumeral, limb-girdle, and ocular muscle types. The main symptoms of this disease are muscle weakness and muscle degeneration. Patients usually have difficulty walking, Achilles tendon contracture, abnormal facial expressions, and in severe cases, they are paralyzed in bed. So, is the probability of inheriting muscular dystrophy high? What is the genetic law of this disease?

1. Muscular dystrophy is very likely to be inherited. This is a hereditary disease whose root cause is a genetic defect, but it is not clear what mechanism affects the muscles. Through electromyography, we can see the manifestations of various types of muscular dystrophy. In order to determine the specific location and inheritance method of the pathogenic gene, the patient also needs to undergo chromosome examination, muscle activity examination, etc.

2. The inheritance of muscular dystrophy. Pseudohypertrophy is inherited in a sex-linked recessive manner. Males are affected and females carry the pathogenic gene. More than half of the patients have varying degrees of heart damage, abnormal electrocardiograms, and early myocardial hypertrophy, but usually no other symptoms except palpitations. If it is the scapulohumeral type, the inheritance is autosomal dominant, and both men and women can get the disease. Mild patients are asymptomatic, and some patients have facial muscle involvement, which manifests as loose eye closure and weak blowing. If it is the limb-girdle type, some cases are inherited in an autosomal recessive manner, and some cases cannot be determined.

The above are the genetic laws of muscular dystrophy, which is a genetic disease with various inheritance modes, including sex-linked recessive inheritance, autosomal dominant inheritance, etc. Patients need to undergo serum enzyme testing, electromyography, and muscle biopsy to diagnose this disease. There is no specific treatment for this disease, and it has been in a state of development since diagnosis, often with lifelong effects. Clinically, in order to improve the quality of life, patients can use adenosine triphosphate, vitamin E, and dexamethasone for treatment. Patients also need to persist in physical exercise to delay muscle atrophy.