What are the three treatments for Kawasaki disease?

What are the three treatments for Kawasaki disease? When it comes to Kawasaki disease, many people may not know much about it. In fact, Kawasaki disease has become more common in recent years. Many parents do not know much about the disease. Once the disease occurs, it will seriously endanger the health of children and needs our attention. When the disease occurs, it must be treated in time. Let’s take a look at the treatments for this disease.

1. Recent studies on immunoglobulin have confirmed that early intravenous infusion of immunoglobulin plus oral aspirin can reduce the incidence of Kawasaki disease coronary artery aneurysm. It must be emphasized that medication should be used within 10 days after onset. The dosage is daily intravenous infusion of immunoglobulin 400 mg/kg, infused over 2 to 4 hours, for 4 consecutive days; at the same time, oral aspirin 50 to 100 mg/kg·d, divided into 3 to 4 times, for 4 consecutive days, and then increased to 5 mg/kg·d, taken all at once.

2. Aspirin. Early oral aspirin can control the acute inflammatory process and reduce coronary artery lesions, but no controlled studies have shown that aspirin treatment can reduce the incidence of coronary artery aneurysms. The dosage is 30-100 mg kg per day, divided into 3-4 times. Japanese doctors tend to use small doses, based on the fact that those who take large doses during the acute phase of Kawasaki disease believe that acute patients have reduced aspirin absorption and increased clearance, and only large doses can achieve anti-inflammatory effects. Take it for 14 days, and after the fever subsides, reduce it to 3-5 mg/kg per day, taken once, and the anti-platelet aggregation effect is fully achieved.

3. Corticosteroids: It has always been believed that adrenal cortex hormones have strong anti-inflammatory effects and can relieve symptoms. However, it was later found that corticosteroids are prone to thrombosis, hinder the repair of coronary artery lesions, and promote aneurysm formation. Therefore, it is not appropriate to use corticosteroids such as prednisone alone for treatment. Unless there is a complication of severe myocarditis or persistent high fever in severe cases, prednisone and aspirin can be used in combination for treatment. In order to control the early inflammatory response of Kawasaki disease, corticosteroids are generally not used alone.

The above content is an introduction to the treatment methods of Kawasaki disease. For the sake of children’s health in life, we must pay attention to it and do corresponding preventive work to reduce the occurrence of the disease. We should also pay more attention to children’s diet and make sure they eat light and easily digestible food.