What are the treatments for patent ductus arteriosus?

What methods are there to treat patent ductus arteriosus? How should we treat patent ductus arteriosus after it occurs? This is also a question that many people want to know, because the incidence of patent ductus arteriosus has been gradually increasing in recent years. Only by understanding the treatment methods can we correctly and scientifically treat it. So, what methods are there to treat patent ductus arteriosus?

Treatment of patent ductus arteriosus:

1. Surgical Method

(1) Simple ligation (double ligation + suture) is a safe, simple and effective method suitable for tubular patent ductus arteriosus.

(2) Catheter anterior wall padding ligation: suitable for children with severe pulmonary hypertension.

(3) Cutting and suturing is ideal, but the operation is more complicated and there is a risk of heavy bleeding.

2. Radiological interventional treatment can now also be used for funnel-shaped patent ductus arteriosus.

3. Treatment of patent ductus arteriosus in premature infants

(1) If the ductus arteriosus does not close at 24 hours after indomethacin treatment and the symptoms do not improve, or if hypoxemia and hypercapnia persist despite adequate ventilation and oxygen support (PC027.98KPA (60MMHG)), simple ductus ligation should be performed urgently.

(2) Indomethacin treatment: Patients who have not responded to anti-heart failure treatment should be given indomethacin by nasogastric feeding. One dose every 8 hours, for a total of 3 times. Before medication, the white blood cell count should be within the normal range, platelets should be no less than 60×109/L (60,000/MM3), urea nitrogen 20MG, and bilirubin 12MG. Urine volume, heart rate, appetite, and jaundice should be observed during medication. After medication, urea nitrogen, electrolytes, echocardiography, and chest X-ray should be reviewed. Adverse reactions of indomethacin include renal failure, hyponatremia, worsening jaundice, bone marrow suppression causing thrombocytopenia and coagulation disorders.

4. Medical treatment: prevent and treat infective endocarditis, respiratory tract infection and heart failure. For premature infants with patent ductus arteriosus, 0.2-0.3 MG/KG of indomethacin or 20 MG/KG of aspirin can be taken orally 4 times a day to inhibit prostaglandin synthesis and close the ductus. For older children or adults with pulmonary hypertension, tamponade or closure agents can be injected through the catheter to block the shunt.

Based on the above introduction, we understand the treatment methods of patent ductus arteriosus. Only when we understand these treatment methods can we detect and treat the disease early and avoid missing the best time for treatment. It is critical to avoid too much harm caused by the occurrence of patent ductus arteriosus and stay away from the disease as early as possible.