What should I do if my newborn baby has jaundice exceeding 400?

What should I do if my newborn baby has jaundice exceeding 400?

Neonatal jaundice of more than 400 umol/L is caused by physiological factors, and may also be caused by pathological factors such as hepatitis and congenital biliary atresia. It can generally be treated by strengthening daily care, drug application, surgery and other methods.

1. Physiological factors:

Neonatal jaundice is generally a neonatal jaundice value within 28 days after birth. If the neonatal jaundice is measured at this time, it is over 400umol/L, which is considered high. Because the newborn is relatively young, the body functions and organs are not yet mature, and the bilirubin is over-produced and the liver processing function is weak, which can cause the jaundice value to be higher than the normal range. This is a physiological factor. Generally, it can return to normal with the increase of age. Usually no special treatment is required, and a reasonable diet is maintained.

2. Pathological factors:

1. Hepatitis:

If a newborn has hepatitis, the continuous stimulation of inflammation will lead to decreased liver function and dysfunction of liver cells in processing bilirubin, which will lead to high neonatal jaundice. If it is a bacterial infection, it will also be accompanied by systemic fatigue. Patients can use cefuroxime sodium, penicillin sodium and azithromycin under the guidance of a doctor.

2. Congenital biliary atresia:

Congenital biliary atresia affects the normal metabolism of bilirubin, resulting in a surge in jaundice levels. It can usually be treated with hepatic portojejunostomy.

In addition to the common causes mentioned above, it may also be caused by hemolytic anemia, which can generally be treated by hematopoietic stem cell transplantation.